√ Garcinia cambogia extract powder (water-soluble)

1. General information and background
Scientific name Garcinia Cambogia
Background: One day, a large man who lived in a mountain village in India went into a mountain and lost his way. After wandering for days, he ate the bark of a tree and returned to his slender body. Then he dried the skin, The dry custard of Garcinia Cambogia has been used as a preservative, spice, and paste for food for centuries throughout the Asia-southeast region.

In 1969, (-) - HCA first acted as an inhibitor of the Krebs / citric acid cycle after its first known effect by the western scientists exploring useful substances at the end of the 1960s In the 1980s, efforts were made to establish physiological functions by American pharmaceutical companies.
Based on these studies, HCA is derived from natural food, has high safety, is not toxic and resistant, and unlike other appetite suppressants on the market, it does not cause symptoms such as insomnia, nervous anxiety, and depression.

2. Functionality
1) Lipid synthesis inhibition
Obesity is caused by the fact that citric acid in the body is degraded by the enzyme called ATP-citrate lyase and becomes fatty acid. However, the combination of HCA and ATP-citrate lyase prevents lipid synthesis.

2) Promote decomposition of fat
In the presence of HCA, citric acid is not degraded and the concentration of malonyl-CoA produced by it decreases. Malonyl-CoA has both the function of synthesis and degradation of fatty acids. When the concentration is lowered, decomposition activity becomes more active than fat synthesis, resulting in promotion of lipolysis.

3) hyperactivity of basal metabolism
In the presence of HCA, the energy of saccharide, accumulation of glycogen, and energy of fat are progressing to some extent at the same time. This is a waste of living energy, but it is effective in consuming accumulated fat. Therefore, it can be assumed that the energy metabolism by the energy consumption is increased.

3. Mechanism
1) The nutrients remaining in the body are used to produce and store body fat through the process of fatty acid production
2) HCA binds to ATP-citrate lyase instead of citrate during body fat synthesis, thereby reducing body fat synthesis
3) Citrate is used as a raw material of glycogen synthesis process to increase glycogen content in the body and to suppress the appetite by allowing the hypothalamus to recognize

4. Intake
1) Functional content: It inhibits the synthesis of carbohydrates into fat and helps reduce body fat.
2) Total daily intake (-) - Hydroxycitric acid 750 ~ 2,800 mg

5. Safety
(154 mmol / kg / diet), HCA was administered at a high concentration (154 mmol/kg / day), and the effect of the intake of the carnitine Cambogia containing the (-) HCA on the female rat was investigated for the purpose of histopathological change, ) Diets were fed for 2 or 4 weeks in female rats and there was no significant difference in sex hormones between the group and the control group, and no morphological abnormality was observed in follicle and corpus luteum.

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